A neuroscientist’s guide to reclaiming your brain

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Your brain is wired to repeat the familiar. Change this wiring, and it will change your life.

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Nicole Vignola, a neuroscientist and organizational psychologist, explains how deeply rooted beliefs can limit our potential and keep us trapped in patterns of thought. These perceptions, often shaped by our upbringing and environment, aren’t necessarily our own—but they can be changed.

Nicole shares how the brain’s natural biases, like negativity bias and confirmation bias, reinforce these limiting beliefs. However, with the right approach, it’s possible to reshape our mental patterns. By practicing metacognition—observing and naming our thoughts—we can start to rewire our perception and create new, empowering narratives.

Our brains are capable of change at any age. By focusing on small wins and challenging automatic thoughts, we can break free from old beliefs and begin using a mindset that better serves ourselves and our futures.

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We created this video in partnership with Unlikely Collaborators.

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About Nicole Vignola:

Nicole Vignola is a neuroscientist, author and corporate consultant. With a BSc in Neuroscience and an MSc in Organizational Psychology, Nicole works with companies and individuals worldwide, educating them on the science of human optimisation, health and longevity, and how to enable employees to perform better in their daily lives and in turn, bring peak performance to the workplace. Recent clients include Lloyds Bank, Makers Mark and Smeg Ltd.